Publication profile
Publication profile
Marit Holden
Name:
Marit Holden
Title:
Sjefsforsker / Chief Research Scientist
Phone:
(+47) +47 22 85 26 77
Email:
marit [at] nr [dot] no
Scientific areas:
Bioinformatics, Functional genomics, Image analysis, Pattern recognition, Deep learning, Markov Chain Monte Carlo (MCMC) simulation,
Homepage:
Public profile

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Academic article
2022
A mammography classification model trained from image labels only. Proceedings of the Northern Lights Deep Learning Workshop. doi: 10.7557/18.6244. 2022.
. 2021
The blood transcriptome prior to ovarian cancer diagnosis: A case-control study in the NOWAC postgenome cohort. PLOS ONE (ISSN 1932-6203). 16:e0256442(8) pp 1-20. doi: 10.1371/journal.pone.0256442. 2021. Arkiv
. Global blood gene expression profiles following a breast cancer diagnosis—Clinical follow-up in the NOWAC post-genome cohort. PLOS ONE (ISSN 1932-6203). 16(3) pp 1-20. doi: 10.1371/journal.pone.0246650. 2021. Arkiv
. Transcriptomic signals in blood prior to lung cancer focusing on time to diagnosis and metastasis. Scientific Reports (ISSN 2045-2322). 11 pp 1-11. doi: 10.1038/s41598-021-86879-8. 2021. Arkiv
. 2020
User-Intended Doppler Measurement Type Prediction Combining CNNs With Smart Post-Processing. IEEE journal of biomedical and health informatics (ISSN 2168-2194). doi: 10.1109/JBHI.2020.3029392. 2020. Arkiv
. Distinct subsets of noncoding RNAs are strongly associated with BMD and fracture, studied in weight-bearing and non-weight-bearing human bone. Journal of Bone and Mineral Research (ISSN 0884-0431). 35(6) pp 1065-1076. doi: 10.1002/jbmr.3974. 2020. Arkiv
. 2019
Automated Left Ventricle Dimension Measurement in 2D Cardiac Ultrasound via an Anatomically Meaningful CNN Approach. Lecture Notes in Computer Science (LNCS) (ISSN 0302-9743). 11798 LNCS pp 29-37. doi: 10.1007/978-3-030-32875-7_4. 2019. Fulltekst
. 2018
Signalling pathways identified in salivary glands from primary Sjögren's syndrome patients reveal enhanced adipose tissue development. Autoimmunity (ISSN 0891-6934). 51(3) pp 135-146. doi: 10.1080/08916934.2018.1446525. 2018.
. Each pregnancy linearly changes immune gene expression in the blood of healthy women compared with breast cancer patients. Clinical Epidemiology (ISSN 1179-1349). doi: 10.2147/CLEP.S163208. 2018. Arkiv
. Climate sensitivity estimates - Sensitivity to radiative forcing time series and observational data. Earth System Dynamics (ESD) (ISSN 2190-4979). 9(2) pp 879-894. doi: 10.5194/esd-9-879-2018. 2018. Arkiv
. 2017
GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome. GigaScience (ISSN 2047-217X). 6(7) pp 1-12. doi: 10.1093/gigascience/gix032. 2017. Arkiv Fulltekst
. Local In Time Statistics for detecting weak gene expression signals in blood – illustrated for prediction of metastases in breast cancer in the NOWAC Post-genome Cohort. Advances in Genomics and Genetics (ISSN 1179-9870). 7 pp 11-28. doi: 10.2147/AGG.S130004. 2017. Arkiv Fulltekst
. 2016
A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle. BMC Medical Research Methodology (ISSN 1471-2288). 16(28) doi: 10.1186/s12874-016-0129-z. 2016. Arkiv
. The PBMC transcriptome profile after intake of oxidized versus high-quality fish oil: an explorative study in healthy subjects. Genes & Nutrition (ISSN 1555-8932). 11:16 doi: 10.1186/s12263-016-0530-6. 2016. Arkiv
. 2015
Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response. Genomics Data (ISSN 2213-5960). 5 pp 176-183. doi: 10.1016/j.gdata.2015.05.019. 2015. Arkiv
. CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray. PLOS ONE (ISSN 1932-6203). 10(2) doi: 10.1371/journal.pone.0117261. 2015. Arkiv
. Age and pro-inflammatory gene polymorphisms influence adjacent segment disc degeneration more than fusion does in patients treated for chronic low back pain. European spine journal (ISSN 0940-6719). pp 2-13. doi: 10.1007/s00586-015-4181-x. 2015.
. Catechol-O-methyltransferase (COMT) gene polymorphisms are associated with baseline disability but not long-term treatment outcome in patients with chronic low back pain. European spine journal (ISSN 0940-6719). 24(11) pp 2425-2431. doi: 10.1007/s00586-015-3866-5. 2015.
. Multi-focus cluster labeling. Journal of Biomedical Informatics (ISSN 1532-0464). 55 pp 116-123. doi: 10.1016/j.jbi.2015.03.012. 2015.
. 2014
A statistical model of ChIA-PET data for accurate detection of chromatin 3D interactions. Nucleic Acids Research (NAR) (ISSN 0305-1048). 42(18) pp e143. doi: 10.1093/nar/gku738. 2014. Fulltekst
. Fish oil supplementation induces Expression of genes related to cell cycle, endoplasmic reticulum stress and apoptosis in peripheral blood mononuclear cells: a transcriptomic approach. Journal of Internal Medicine (ISSN 0954-6820). 276(5) pp 498-511. doi: 10.1111/joim.12217. 2014. Arkiv
. Evaluation of Binary Descriptors for Fast and Fully Automatic Identification. International Conference on Pattern Recognition (ISSN 1051-4651). pp 154-159. doi: 10.1109/ICPR.2014.36. 2014.
. A lower and more constrained estimate of climate sensitivity using updated observations and detailed radiative forcing time series. Earth System Dynamics (ESD) (ISSN 2190-4979). 5(1) pp 139-175. doi: 10.5194/esd-5-139-2014. 2014.
. 2013
The Genomic HyperBrowser: an analysis web server for genome-scale data. Nucleic Acids Research (NAR) (ISSN 0305-1048). 41(W1) pp W133-W141. doi: 10.1093/nar/gkt342. 2013. Arkiv
. Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer. PLOS ONE (ISSN 1932-6203). 8(6) doi: 10.1371/journal.pone.0066165. 2013.
. Treatment outcome of chronic low back pain and radiographic lumbar disc degeneration are associated with inflammatory and matrix degrading gene variants: a prospective genetic association study. BMC Musculoskeletal Disorders (ISSN 1471-2474). 14(105) doi: 10.1186/1471-2474-14-105. 2013.
. Identification of eight candidate target genes of the recurrent 3p12p14 loss in cervical cancer by integrative genomic profiling. Journal of Pathology (ISSN 0022-3417). 230(1) pp 59-69. doi: 10.1002/path.4168. 2013.
. 2012
Stress associated gene expression in blood cells is related to outcome in radiotherapy treated head and neck cancer patients. BMC Cancer (ISSN 1471-2407). 12 doi: 10.1186/1471-2407-12-426. 2012.
. Hypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast enhanced MRI. Cancer Research (ISSN 0008-5472). 72(20) pp 5285-5295. doi: 10.1158/0008-5472.CAN-12-1085. 2012.
. Bayesian estimation of climate sensitivity based on a simple climate model fitted to observations of hemispheric temperatures and global ocean heat content. Environmetrics (ISSN 1180-4009). 23(3) pp 253-271. doi: 10.1002/env.2140. 2012.
. Genetic contribution of catechol-O-methyltransferase variants in treatment outcome of low back pain: a prospective genetic association study. BMC Musculoskeletal Disorders (ISSN 1471-2474). 13 doi: 10.1186/1471-2474-13-76. 2012.
. 2011
The differential disease regulome. BMC Genomics (ISSN 1471-2164). 12 pp 353. doi: 10.1186/1471-2164-12-353. 2011. Fulltekst
. Membranous Expression of Ectodomain Isoforms of the Epidermal Growth Factor Receptor Predicts Outcome after Chemoradiotherapy of Lymph Node-Negative Cervical Cancer. Clinical Cancer Research (ISSN 1078-0432). 17(16) pp 5501-5512. doi: 10.1158/1078-0432.CCR-11-0297. 2011.
. Molecular Disease Map of Bone Characterizing the Postmenopausal Osteoporosis Phenotype. Journal of Bone and Mineral Research (ISSN 0884-0431). 26(8) pp 1793-1801. doi: 10.1002/jbmr.396. 2011.
. 2010
The Genomic HyperBrowser: inferential genomics at the sequence level. Genome Biology (ISSN 1465-6906). 11(12) doi: 10.1186/gb-2010-11-12-r121. 2010. Prosjekt Arkiv
. Eight genes are highly associated with BMD variation in postmenopausal Caucasian women. Bone (ISSN 8756-3282). 46(3) pp 604-612. doi: 10.1016/j.bone.2009.11.007. 2010.
. Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers. BMC Medicine (ISSN 1741-7015). 8 doi: 10.1186/1741-7015-8-54. 2010.
. 2009
Gene Dosage, Expression, and Ontology Analysis Identifies Driver Genes in the Carcinogenesis and Chemoradioresistance of Cervical Cancer. PLoS Genetics (ISSN 1553-7390). 5(11) doi: 10.1371/journal.pgen.1000719. 2009.
. ADAPTIVE INDEPENDENT METROPOLIS-HASTINGS. The Annals of Applied Probability (ISSN 1050-5164). 19(1) pp 395-413. doi: 10.1214/08-AAP545. 2009. Fulltekst
. 2008
Validation of oligoarrays for quantitative exploration of the transcriptome. BMC Genomics (ISSN 1471-2164). 9 doi: 10.1186/1471-2164-9-258. 2008.
. GSEA-SNP: applying gene set enrichment analysis to SNP data from genome-wide association studies. Bioinformatics (ISSN 1367-4803). 24(23) pp 2784-2785. doi: 10.1093/bioinformatics/btn516. 2008.
. 2007
Cord blood gene expression in infants hospitalized with respiratory syncytial virus bronchiolitis. Journal of Infectious Diseases (ISSN 0022-1899). 196 doi: 10.1086/519168. 2007.
. 2006
Whole blood gene expression in infants with respiratory syncytial virus bronchiolitis. BMC Infectious Diseases (ISSN 1471-2334). 6 doi: 10.1186/1471-2334-6-175. 2006.
. Sampling effects on gene expression data from a human tumour xenograft. Scandinavian Journal of Laboratory Animal Science (ISSN 0901-3393). 33 pp 17-34. 2006.
. 2005
Limitations of mRNA amplification from small-size cell samples. BMC Genomics (ISSN 1471-2164). (6) pp 147. doi: 10.1186/1471-2164-6-147. 2005.
. Genome-wide estimation of transcript concentrations from spotted cDNA microarray data. Nucleic Acids Research (NAR) (ISSN 0305-1048). 33(17) doi: 10.1093/nar/gni141. 2005.
. Bayesian population dynamics of interacting species: Great gerbils and fleas in Kazakhstan. Biometrics (ISSN 0006-341X). 61 2005.
. 2004
Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method. Proteomics (ISSN 1615-9853). 4 pp 2572-2582. 2004.
. 2003
Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance. BMC Genomics (ISSN 1471-2164). 4(11) doi: 10.1186/1471-2164-4-11. 2003. Sammendrag Sammendrag
. Comment on Cowling's "Spatial Methods for Line Transect Surveys". Biometrics (ISSN 0006-341X). 59 pp 186-188. 2003.
. 1998
Wet snow-cover mapping by C- and L-band polarimtric SAR. Ukjent 1998.
.
. 1997
Examples of use of cut to shorten proofs. Ukjent 1997.
. 1995
Segmentation and visualization of brain lesions in multispectral magnetic resonance images. Computerized Medical Imaging and Graphics (ISSN 0895-6111). 19(2) pp 171-173. 1995.
. Automatic recognition of character strings in maps. Ukjent 1995.
. 1993
Methods for updating of model parameters applied within the area of symbol recognition. Ukjent 1993.
. 1991
Weak logic theory. Theoretical Computer Science (ISSN 0304-3975). 79 pp 295-321. 1991.
. Academic literature review
2009
Adaptive registration of remote sensing images using supervised learning. Photogrammetric Engineering and Remote Sensing (ISSN 0099-1112). 75(11) pp 1297-1306. 2009. Fulltekst
. Academic chapter/article/Conference paper
2020
Signals of Death - Post-Diagnostic Single Gene Expression Trajectories in Breast Cancer - A Proof of Concept. In: Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression. (ISBN 978-82-15-04119-3). pp 141-162. doi: 10.18261/9788215041193-2020-09. 2020. Arkiv
. Statistics of Sparsely Sampled Curves. In: Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression. (ISBN 978-82-15-04119-3). pp 95-109. doi: 10.18261/9788215041193-2020-06. 2020. Fulltekst
. 2006
Bayesian process-based modeling of two-channel microarray experiments estimating absolute mRNA concentrations. In: Bayesian Inference for Gene Expression and Proteomics. (ISBN 978-0-521-86092-5). pp 75-97. 2006.
. Academic lecture
2022
Context-Aware Landmark Detection for 2D Cardiac Ultrasound using Graph Convnet. GEVU Research Day; Teams, 5/23/2022.
. 2021
Learning motion of seismic structures without human labelling. Visual Intelligence Days 2021; Oslo, 10/19/2021 - 10/20/2021.
. 2014
Evaluation of binary descriptors for fast and fully automatic identification. International Conference on Pattern Recognition; Stockholm, 8/24/2014 - 8/28/2014.
. 2011
Statistics Forelesning kurs. Introduction to Microarray Technology; Oslo, 5/10/2011.
. 2010
Bayesian estimation of the climate sensitivity based on a simple climate model fitted to global temperature observations. International Workshop on Modern Statistics for Climate Research; Oslo, 2/1/2010 - 2/2/2010.
. Postmenopausal BMD Variation is Strongly Associated with Subsets of MicroRNAs and Other Non-coding RNAs (ncRNAs) Expression Levels. The American Society for Bone and Mineral Research, Annual Meeting, 2010, Toronto, Ontario, Canada, 10/16/2010.
. 2009
A system for adaptive image registration based on supervised learning. ESA-EUSC-JRC 2009, Sixth Conferenece on Image Information Mining, Madrid, 3-5 Nov. 2009, 11/4/2009. Fulltekst
. 2008
Plant food phytochemicals modulate gene expression in human blood cells. 5th European nutrigenomics conference; potsdam, 9/2/2008 - 9/5/2008.
. Adaptive Co-Registration of Remote Sensing Images. ESA-EUSC 2008: Image Information Mining: pursuing automation of geospatial intelligence for environm, 3/6/2008. Fulltekst
. Vehicle Detection in High-Resolution Satellite Images. ESA-EUSC 2008: Image Information Mining: pursuing automation of geospatial intelligence for environm, 3/6/2008. Fulltekst
. 2006
Steps in a microarray study. Seminar on microarray technologies arranged by the Rikshospitalet-Radiumhospitalet Medical Center; Oslo, 11/24/2006.
. Parallelization of TransCount - making MCMC parallel for huge datasets. High Performance Computing for Statistical Inference, Dublin, August 23-25, 2006, 8/23/2006.
. 2005
Model-based estimation of transcript concentrations from spotted microarray data. 25th European Meeting of Statisticians, July 24-28, 2005, Oslo, Norway, 7/24/2005.
. Logic regression used for statistical analysis of SNP data obtained in genetic association studies. Talk at UMB, Ås, 6/14/2005.
. Experimental design and non-random variation. Lecture at the course \Micorarray data analysis\" at the Norwegian Radium Hospital, Oslo,", 5/31/2005.
. 2004
Introduction to experimental design and statistical analysis in genetic association studies. Reach-out day with theme: Statistical service on experimental design and analysis of SNP experiments, 5/1/2004.
. Experimental design, repeated measurements and control spots. Course in analysis of microarray data; Bergen, 2/3/2004.
. Experimental design and non-random variation. Introduction to Microarray Technology; The Norwegian Radium Hospital, Oslo, 11/29/2004.
. 2003
Forsøksdesign for cDNA mikromatriser. Foredrag. Ahus (Universitetssykehuset i Akershus), 12/1/2003.
. Experimental design, repeated measurements and controls. User course in microarray technology; The Norwegian Radium Hospital, Oslo, 5/14/2003.
. Experimental design, repeated measurements and control spots. User course in microarray technology; The Norwegian Radium Hospital, Oslo, 5/14/2003.
. Estimation of absolute mRNA concentrations from cDNA microarrays. Norevent's 3rd Lysebu meeting, 9/1/2003.
. 2002
Investigating the linearity of an RNA-amplification protocol using analysis of variance on data from cDNA microarray experiments. 19th Nordic Conference on Mathematical Statistics, 6/9/2002.
. Bildeanalyse av mikromatrisedata. NOBIMs industriseminar i bildeanalyse. Tønsberg, 10/24/2002.
. 2000
A new method for sub-pixel snow-cover mapping using hyperspectral imagery. NOBIM-konferansen, 6/6/2000. Fulltekst
. 1998
Segmentation and Visualization of Brain Lesions in Multispectral Magnetic Resonance Images. Workshop on Models and Methods for Spatial and Spatio-temporal Data, München,, 10/19/1998.
. 1993
Methods for updating of model parameters applied within the area of symbol recognition. The 8th SCIA Conference; Tromsø, Norway, 1/1/1993.
. 1992
Oppdatering av parameterestimater. Bildebehandlingsseminar; Institutt for Informatikk, Universitetet i Oslo, 11/9/1992.
. Abstract
2018
Distinct subsets of non-coding RNAs, including miRNAs, are associated with BMD in stressed and unstressed bone. Journal of Bone and Mineral Research. 33 pp 228. 2018. Omtale
. Lecture
2019
Maskinlæring i mammografiprogrammet. Fagkonferansen i mammografiprogrammet, 3/28/2019 - 3/29/2019.
. 2018
Advising in a research institute: Challenges and lessons learned. ADVICE 2018, 11/10/2018 - 11/11/2018.
. 2017
Subtle alterations in gene expression detected in blood prior to metastatic lung cancer diagnosis – the NOWAC study. The 24th Norwegian Epidemiology Conference; Tromsø, 11/7/2017 - 11/8/2017.
. Poster
2022
A two-stage mammography classification model using XAI for ROI detection. Visual Intelligence days 2022; Olavsgaard, 9/28/2022 - 9/29/2022.
. A mammography classification model trained from image labels only. NLDL 2022; Online, 1/10/2022.
. Context-Aware Landmark Detection for 2D Cardiac Ultrasound using a Graph Convolution Network. Northern Lights Deep Learning conference, 1/10/2022 - 1/12/2022.
. 2019
Post-diagnostic blood gene expression profiles in breast cancer - NOWAC Post-genome Cohort. NOFE conference; Oslo, 11/13/2019 - 11/14/2019.
. 2018
Transcriptional profiles of whole blood before a diagnosis of ovarian cancer. NOFE-konferansen 2018; Trondheim, 11/14/2018 - 11/15/2018.
. Distinct subsets of non-coding RNAs, including miRNAs, are associated with BMD in stressed and unstressed bone. ASBMR Annual meeting 2018; Montreal, 9/28/2018 - 10/1/2018.
. 2016
Blood gene expression profiles reflect temporality and clinical parameters up to six years before breast cancer diagnosis – The Norwegian. Norsk Forening for epidemiologi; Bergen, 9/26/2016 - 9/27/2016.
. Blood gene expression profiles reflect temporality and clinical parameters up to six years before breast cancer diagnosis – The Norwegian Women and Cancer Post-genome cohort (Kvinner og Kreft-studien). 1st International NTNU Symposium on clinical biomarkers of cancer; Trondheim, 6/16/2016 - 6/17/2016.
. 2012
Constraining climate sensitivity by observations and models. European Geosciences Union General Assembly 2012; Wien, 4/22/2012 - 4/27/2012.
. 2009
Eight Genes are Highly Associated with BMD variation in Postmenopausal Caucasian Women. 31th Annual meeting of the American Society for Bone and Mineral Research Denver Colorado 2009, 9/11/2009 - 9/15/2009.
. 2005
Absolute mRNA concentrations from MA-data. 8th International Meeting of the Microarray Gene Expression Data Society, 9/11/2005.
. Report
2022
Procedures for mammographic screening with machine learning. Norsk Regnesentral. NR-notat SAMBA/17/22. pp 16. 2022.
. Machine learning for screening mammography. Norsk Regnesentral. NR-notat SAMBA/18/22. pp 33. 2022.
. Learning motion of seismic structures without human labelling. Norsk Regnesentral. NR-notat SAMBA/10/22. pp 22. 2022.
. 2021
Machine learning for image-based interpretation of non-verbal communication. Norsk Regnesentral. NR-notat SAMBA/04/21. pp 37. 2021.
. Machine learning for screening mammography. Norsk Regnesentral. NR-notat SAMBA/05/21. pp 52. 2021.
. Machine learning for image-based interpretation of non-verbal communication - Initial version. Norsk Regnesentral. NR-notat SAMBA/04/21. pp 37. 2021.
. 2020
Deep learning in seismic interpretations - Development and experiments 2020. Norsk Regnesentral. NR-notat SAMBA/51/20. pp 26. 2020.
. Machine learning for screening mammography - Initial analyses on a first limited dataset. Norsk Regnesentral. NR-notat SAMBA/16/20. pp 45. 2020.
. 2019
Estimation of rock cuttings size from images. Norsk Regnesentral. NR-notat SAND/02/2019. pp 43. 2019.
. Deep learning in seismic interpretation. Norsk Regnesentral. NR-notat SAMBA/49/19. pp 39. 2019.
. Deep learning for ultrasound images - next steps. Norsk Regnesentral. NR-notat SAMBA/48/19. pp 55. 2019.
. BLOBREC – a blood-based test for breast cancer Analyses of test properties in the years before and after diagnosis. Norsk Regnesentral. NR-notat SAMBA/27/19. pp 17. 2019. Fulltekst
. Parity and breast cancer Gene expression in blood, normal and tumor tissue. Norsk Regnesentral. NR-notat SAMBA/24/19. pp 30. 2019.
. 2018
Deep learning for ultrasound images. Norsk Regnesentral. NR-notat SAMBA/24/18. pp 92. 2018.
. Parity and breast cancer - Gene expression in blood, normal and tumor tissue. Norsk Regnesentral. NR-notat SAMBA/02/18. pp 25. 2018.
. 2016
Smoothing of forward curves. Norsk Regnesentral. NR-notat SAMBA/25/16. pp 22. 2016.
. Detecting weak gene expression signals in blood before diagnosis of cancer - Comparing breast, ovarian and lung cancer. Norsk Regnesentral. NR-notat SAMBA/28/16. pp 32. 2016.
. Fjerning av støy fra historiske dokumenter. Norsk Regnesentral. NR-notat SAMBA/24/16. pp 38. 2016.
. Parity, breast cancer and gene expression. Norsk Regnesentral. NR-notat SAMBA/19/16. pp 25. 2016.
. Analysis of gene expression in blood before diagnosis of ovarian cancer - Different statistical methods. Norsk Regnesentral. NR-notat SAMBA/10/16. pp 36. 2016. Fulltekst
. Statistical analysis of gene expression in blood before diagnosis of breast cancer. Norsk Regnesentral. NR-notat SAMBA/07/16. pp 39. 2016. Fulltekst
. 2015
Blood-based diagnostic tests for breast cancer:Additional subgroup analyses of the BLOBREC test. Norsk Regnesentral. NR-notat SAMBA/44/15. pp 30. 2015.
. Verification of a blood-based test for breast-cancer (BLOBREC) - Distinguishing breast-cancer patients from population-based controls. Norsk Regnesentral. NR-notat SAMBA/33/15. pp 36. 2015. Fulltekst
. Verifikasjon av strekkoder. Norsk Regnesentral. NR-notat SAMBA/36/15. pp 41. 2015.
. Utvalg av deskriptorer for oppbygging av database. Norsk Regnesentral. NR-notat SAMBA/25/15. pp 27. 2015.
. Bruk av fargedeskriptorer for gjenkjenning av ukeblader. Norsk Regnesentral. NR-notat SAMBA/19/15. pp 30. 2015.
. Curve groups and breast cancer. Norsk Regnesentral. NR-notat SAMBA/18/15. pp 32. 2015.
. 2014
Statistical analysis of gene expression data related to breast cancer diagnosis. Norsk Regnesentral. NR-notat SAMBA/19/14. pp 74. 2014. Fulltekst
. Historisk informasjon fra avisarkiv. Norsk Regnesentral. NR-notat SAMBA 51/14. pp 41. 2014.
. Preprocessing of gene-expression data related to breast cancer diagnosis – extended version. Norsk Regnesentral. NR-notat SAMBA/32/14. 2014.
. Preprocessing of gene-expression data related to breast cancer diagnosis. Norsk Regnesentral. NR-notat SAMBA/35/14. pp 41. 2014.
. Robust klassifikasjon av ukeblader. Norsk Regnesentral. NR-notat SAMBA/17/14. pp 18. 2014.
. 2013
Descriptors and matching for real-time recognition of planar and curved objects. Norsk Regnesentral. NR-notat SAMBA/3/13. pp 39. 2013.
. Metoder og programmer for gjenkjenning av ukeblader. Norsk Regnesentral. NR-notat SAMBA/19/13. pp 18. 2013.
. 2012
Detectors and descriptors for real-time recognition of planar objects. Norsk Regnesentral. NR-notat SAMBA/03/12. pp 23. 2012.
. Detecting beads in time series of DNA-sequencing images. Norsk Regnesentral. NR-notat SAMBA/57/12. pp 35. 2012.
. Image restoration and analysis of biomolecular radioactivity images II. Norsk Regnesentral. NR-notat SAMBA/11/12. pp 48. 2012.
. ProPrice Interface Specification. Norsk Regnesentral. NR-notat SAMBA/29/12. pp 19. 2012.
. Importance Sampling from DNB's Credit Risk Model. Norsk Regnesentral. NR-notat SAMBA/31/12. pp 30. 2012.
. 2011
Bildeanalyse av røntgenbilder til hjelp for aldersvurdering. Norsk Regnesentral. NR-notat SAMBA/43/11. pp 28. 2011. Fulltekst
. Parallellisering av Totalrisiko-programmet ved hjelp av GPU. Norsk Regnesentral. NR-notat SAMBA/13/2011. pp 14. 2011.
. Parallellisering av simulering fra vines. Norsk Regnesentral. NR-notat SAMBA/18/2011. pp 13. 2011.
. Efficient search for biomedical information. Norsk Regnesentral. NR-notat SAMBA/54/11. pp 45. 2011.
. 2010
Parallellisering av Totalrisiko-programmet. Norsk Regnesentral. NR-notat SAMBA/43/10. pp 14. 2010.
. Parallellisering av Kredittrisiko-programmet. Norsk Regnesentral. NR-notat SAMBA/49/10. pp 16. 2010.
. 2009
MIR - Multiple Image Registration, Technical Documentation. Norsk Regnesentral. NR-notat SAMBA/12/09. pp 160. 2009.
. MIR - Multiple Image Registration, Software Documentation. Norsk Regnesentral. NR-notat SAMBA/11/09. pp 138. 2009.
. 2008
CultSearcher – Software Guide, version 2. Computer-assisted detection of potential cultural heritage sites. Norsk Regnesentral. NR-notat SAMBA/15/08. pp 42. 2008. Fulltekst
. Image restoration and analysis of biomolecular radioactivity images. Norsk Regnesentral. NR-notat SAMBA/27/08. pp 34. 2008. Fulltekst
. 2007
CultSearcher - Computer-assisted detection of potential cultural heritage sites. Norsk Regnesentral. NR-notat SAMBA/39/07. pp 39. 2007.
. Road Traffic Snapshot. Norsk Regnesentral. Report at the Norwegian Computing Center 1015. (ISBN 978-82-539-0525-9) pp 71. 2007. Fulltekst
. 2004
Model-based estimation of transcript concentrations from spotted microarray data. Norsk Regnesentral. Report at the Norwegian Computing Center 999. (ISBN 82-539-0507-6) pp 40. 2004. Fulltekst Fulltekst
. glme: a C-program for parameter estimation using Gibbs-sampling in large linear mixed-effects models, with applications to DNA microarray data. Department of Mathematical Sciences, NTNU. Preprint Series in Statistics 2/2004. pp 20. 2004. Fulltekst
. 2003
A Bayesian model for the population dynamics of two interacting species, with application to great gerbils and fleas in south-eastern Kazakhstan. Norsk Regnesentral. Report at the Norwegian Computing Center 994. (ISBN 82-539-0501-7) pp 19. 2003.
. Experimental design and statistical analysis of SNP data obtained in genetic association studies. Norsk Regnesentral. NR-notat SAMBA/28/03. pp 32. 2003. Fulltekst
. 2001
Estimation of a Neyman-Scott process from line transect data by a one-dimensional K-function. Norsk Regnesentral. NR-notat SAMBA/18/01. pp 11. 2001. Fulltekst
. 2000
Plague in Kazakhstan: a bayesian model for the temporal dynamics of a vector-transmitted infectious disease. Norsk Regnesentral. Report at the Norwegian Computing Center 959. (ISBN 82-539-0463-0) pp 20. 2000.
. Locating pipes in cross-profiles - documentation of methods and results. Norsk Regnesentral. NR-notat SAMBA/21/00. pp 23. 2000.
. Locating pipes in cross-profiles - documentation of C++ code. Norsk Regnesentral. NR-notat SAMBA/22/00. pp 29. 2000.
. SnowStar - Teknisk dokumentasjon for SnowStar Server. Norsk Regnesentral. NR-notat SAMBA/29/00. pp 18. 2000.
. SnowStar - Brukerveiledning for SnowStar Server. Norsk Regnesentral. NR-notat SAMBA/28/00. pp 18. 2000.
. 1999
Seismic Attribute Analysis, Part IV. Norsk Regnesentral. NR-notat SAMBA/17/99. pp 76. 1999.
. 1998
Seismic image analysis: 3D texture attributes and classification - part III. Norsk Regnesentral. NR-notat SAMBA/21/98. 1998.
. Snow mapping by multifrequency polarimetric SAR - An investigation of EMISAR data from the EMAC'95 snow campaign in Norway. 934. (ISBN 82-539-0417-7) 1998.
. 1997
Seismic image analysis: 3D texture attributes and classification - part II. Norsk Regnesentral. NR-notat BILD/07/97. pp 60. 1997.
. 1994
Automatic interpretation of incoming mail in administrative environments. Norsk Regnesentral. NR-notat BILD/04/94. pp 21. 1994.
. Segmentation of MR images of the head using a hierarchical method. 881. (ISBN 82-539-0377-4) pp 25. 1994.
. 1993
Segmentation and visualization of brain lesions in multispectral magnetic resonance images. Norsk Regnesentral. (ISBN 82-539-0367-7) pp 37. 1993.
. Assessment of tissue perfusion and characterization of lesions in dynamical MRI using contrast agents and statistical analysis - methodological considerations and clinical applications. Norsk Regnesentral. NR-notat BILD/10/93. pp 70. 1993.
. Diagnostic evaluation of contrast agents in medical imaging - proposals towards quantitative assessment. Norsk Regnesentral. NR-notat BILD/03/93. pp 100. 1993.
. Theory and methods for automatic training and updating. Norsk Regnesentral. NR-notat BILD/08/93. pp 26. 1993.
. Image acquisition and pre-processing methods for machine vision sensors. 864. (ISBN 82-539-0358-8) pp 63. 1993.
. 1992
Analysis of frequency information in echocardiographic radio-frequency data acquired in the presence or absance of a contrast agent (Albunex). Norsk Regnesentral. NR-notat BILD/04/92. 1992.
. An evaluation of statistical modeling in magnetic resonance imaging using images fron the central nervous system aquired with and without a Gladolium-based contrast medium. Norsk Regnesentral. Report at the Norwegian Computing Center 855. (ISBN 82-539-0348-0) pp 47. 1992.
. Multispectral analysis and classification system (cxxmacs): Users manual. Norsk Regnesentral. Report at the Norwegian Computing Center 863. (ISBN 82-539-0356-1) pp 86. 1992.
. Methods for updating of model parameters applied within the area of symbol recognition. Norsk Regnesentral. Report at the Norwegian Computing Center 859. (ISBN 82-539-0352-9) pp 30. 1992.
. Improving statistical image classification by updating model parameters using unclassified pixels. Norsk Regnesentral. Report at the Norwegian Computing Center 857. (ISBN 82-539-0350-2) pp 26. 1992.
. Popular scientific lecture
2009
Introductory microarray course; statistics. , .
. 2008
Introductory microarray course; statistics. , .
. 2006
Finding differentially expressed genes from microarray data. , .
. 2005
Statistics and Bioinformatics. , .
. Funksjonell genomforskning, bioinformatikk og statistikk. Temakveld om bioinformatikk/medisinsk statistikk, Norsk Statistisk Forening avdeling Oslo, 11/30/2005.
. 2004
Course in statistics for molecular biologists. Bergen, 12/7/2004.
. 2002
Klustring av mikromatrisedata. Kurs for Interagon, 4/18/2002.
. Article in business/trade/industry journal
2022
Trajectories of gene expression, seasonal influenza, and within-host seasonal immunity: transfer value to covid-19. medRxiv doi: 10.1101/2022.03.01.22271679. 2022. Fulltekst
. 2003
Introduksjon til analyse av cDNA mikromatrisedata. Norsk Epidemiologi (ISSN 0803-2491). pp 132291-296. 2003.
. 2002
Spatial distribution of whales based on the Norwegian Minke Whale Survey 1996-2001. Ukjent 2002. Fulltekst
. 1997
Use of cut to obtain a characterization of the Kalmar elementary functions. Technical Report Department of Informatics (254, ISBN 82-7368-174-2) 1997.
. 1996
A proof theoretic characterization of the Kalmar elementary functions. Technical Report Department of Informatics (211, ISBN 82-7368-124-6) 1996.
. 1988
Weak logic theory. Doctor Scient Thesis (111) 1988.
. 1986
Theorem proving in classical logic applied within a logic for system specification. Research Report, Department of Informatics, University of Oslo (99) 1986.
. 1985
Bevisføring i klassisk logikk anvendt innenfor en logikk for systemspesifikasjon. Cand. Scient thesis 1985.
. Popular scientific article
2012
Using modelled historical concentrations of short lived climate components to constrain the climate sensitivity. META (ISSN 1890-1956). (2) pp 8-11. 2012.
. 1994
Characterization of lesions in dynamical MRI using contrast agent and statistical analysis. Ukjent pp 123-127. 6/14/1994.
. Reader opinion piece
2006
Bioinformatikk-et tverrfaglig forskningsfelt. Tilfeldig gang, 12/5/2006,
.

Name: | Marit Holden |
Title: | Sjefsforsker / Chief Research Scientist |
Phone: | (+47) +47 22 85 26 77 |
Email: | marit [at] nr [dot] no |
Scientific areas: | Bioinformatics, Functional genomics, Image analysis, Pattern recognition, Deep learning, Markov Chain Monte Carlo (MCMC) simulation, |
Homepage: | Public profile |
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Show publications |
Academic article
2022
A mammography classification model trained from image labels only. Proceedings of the Northern Lights Deep Learning Workshop. doi: 10.7557/18.6244. 2022.
. 2021
The blood transcriptome prior to ovarian cancer diagnosis: A case-control study in the NOWAC postgenome cohort. PLOS ONE (ISSN 1932-6203). 16:e0256442(8) pp 1-20. doi: 10.1371/journal.pone.0256442. 2021. Arkiv
. Global blood gene expression profiles following a breast cancer diagnosis—Clinical follow-up in the NOWAC post-genome cohort. PLOS ONE (ISSN 1932-6203). 16(3) pp 1-20. doi: 10.1371/journal.pone.0246650. 2021. Arkiv
. Transcriptomic signals in blood prior to lung cancer focusing on time to diagnosis and metastasis. Scientific Reports (ISSN 2045-2322). 11 pp 1-11. doi: 10.1038/s41598-021-86879-8. 2021. Arkiv
. 2020
User-Intended Doppler Measurement Type Prediction Combining CNNs With Smart Post-Processing. IEEE journal of biomedical and health informatics (ISSN 2168-2194). doi: 10.1109/JBHI.2020.3029392. 2020. Arkiv
. Distinct subsets of noncoding RNAs are strongly associated with BMD and fracture, studied in weight-bearing and non-weight-bearing human bone. Journal of Bone and Mineral Research (ISSN 0884-0431). 35(6) pp 1065-1076. doi: 10.1002/jbmr.3974. 2020. Arkiv
. 2019
Automated Left Ventricle Dimension Measurement in 2D Cardiac Ultrasound via an Anatomically Meaningful CNN Approach. Lecture Notes in Computer Science (LNCS) (ISSN 0302-9743). 11798 LNCS pp 29-37. doi: 10.1007/978-3-030-32875-7_4. 2019. Fulltekst
. 2018
Signalling pathways identified in salivary glands from primary Sjögren's syndrome patients reveal enhanced adipose tissue development. Autoimmunity (ISSN 0891-6934). 51(3) pp 135-146. doi: 10.1080/08916934.2018.1446525. 2018.
. Each pregnancy linearly changes immune gene expression in the blood of healthy women compared with breast cancer patients. Clinical Epidemiology (ISSN 1179-1349). doi: 10.2147/CLEP.S163208. 2018. Arkiv
. Climate sensitivity estimates - Sensitivity to radiative forcing time series and observational data. Earth System Dynamics (ESD) (ISSN 2190-4979). 9(2) pp 879-894. doi: 10.5194/esd-9-879-2018. 2018. Arkiv
. 2017
GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome. GigaScience (ISSN 2047-217X). 6(7) pp 1-12. doi: 10.1093/gigascience/gix032. 2017. Arkiv Fulltekst
. Local In Time Statistics for detecting weak gene expression signals in blood – illustrated for prediction of metastases in breast cancer in the NOWAC Post-genome Cohort. Advances in Genomics and Genetics (ISSN 1179-9870). 7 pp 11-28. doi: 10.2147/AGG.S130004. 2017. Arkiv Fulltekst
. 2016
A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle. BMC Medical Research Methodology (ISSN 1471-2288). 16(28) doi: 10.1186/s12874-016-0129-z. 2016. Arkiv
. The PBMC transcriptome profile after intake of oxidized versus high-quality fish oil: an explorative study in healthy subjects. Genes & Nutrition (ISSN 1555-8932). 11:16 doi: 10.1186/s12263-016-0530-6. 2016. Arkiv
. 2015
Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response. Genomics Data (ISSN 2213-5960). 5 pp 176-183. doi: 10.1016/j.gdata.2015.05.019. 2015. Arkiv
. CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray. PLOS ONE (ISSN 1932-6203). 10(2) doi: 10.1371/journal.pone.0117261. 2015. Arkiv
. Age and pro-inflammatory gene polymorphisms influence adjacent segment disc degeneration more than fusion does in patients treated for chronic low back pain. European spine journal (ISSN 0940-6719). pp 2-13. doi: 10.1007/s00586-015-4181-x. 2015.
. Catechol-O-methyltransferase (COMT) gene polymorphisms are associated with baseline disability but not long-term treatment outcome in patients with chronic low back pain. European spine journal (ISSN 0940-6719). 24(11) pp 2425-2431. doi: 10.1007/s00586-015-3866-5. 2015.
. Multi-focus cluster labeling. Journal of Biomedical Informatics (ISSN 1532-0464). 55 pp 116-123. doi: 10.1016/j.jbi.2015.03.012. 2015.
. 2014
A statistical model of ChIA-PET data for accurate detection of chromatin 3D interactions. Nucleic Acids Research (NAR) (ISSN 0305-1048). 42(18) pp e143. doi: 10.1093/nar/gku738. 2014. Fulltekst
. Fish oil supplementation induces Expression of genes related to cell cycle, endoplasmic reticulum stress and apoptosis in peripheral blood mononuclear cells: a transcriptomic approach. Journal of Internal Medicine (ISSN 0954-6820). 276(5) pp 498-511. doi: 10.1111/joim.12217. 2014. Arkiv
. Evaluation of Binary Descriptors for Fast and Fully Automatic Identification. International Conference on Pattern Recognition (ISSN 1051-4651). pp 154-159. doi: 10.1109/ICPR.2014.36. 2014.
. A lower and more constrained estimate of climate sensitivity using updated observations and detailed radiative forcing time series. Earth System Dynamics (ESD) (ISSN 2190-4979). 5(1) pp 139-175. doi: 10.5194/esd-5-139-2014. 2014.
. 2013
The Genomic HyperBrowser: an analysis web server for genome-scale data. Nucleic Acids Research (NAR) (ISSN 0305-1048). 41(W1) pp W133-W141. doi: 10.1093/nar/gkt342. 2013. Arkiv
. Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer. PLOS ONE (ISSN 1932-6203). 8(6) doi: 10.1371/journal.pone.0066165. 2013.
. Treatment outcome of chronic low back pain and radiographic lumbar disc degeneration are associated with inflammatory and matrix degrading gene variants: a prospective genetic association study. BMC Musculoskeletal Disorders (ISSN 1471-2474). 14(105) doi: 10.1186/1471-2474-14-105. 2013.
. Identification of eight candidate target genes of the recurrent 3p12p14 loss in cervical cancer by integrative genomic profiling. Journal of Pathology (ISSN 0022-3417). 230(1) pp 59-69. doi: 10.1002/path.4168. 2013.
. 2012
Stress associated gene expression in blood cells is related to outcome in radiotherapy treated head and neck cancer patients. BMC Cancer (ISSN 1471-2407). 12 doi: 10.1186/1471-2407-12-426. 2012.
. Hypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast enhanced MRI. Cancer Research (ISSN 0008-5472). 72(20) pp 5285-5295. doi: 10.1158/0008-5472.CAN-12-1085. 2012.
. Bayesian estimation of climate sensitivity based on a simple climate model fitted to observations of hemispheric temperatures and global ocean heat content. Environmetrics (ISSN 1180-4009). 23(3) pp 253-271. doi: 10.1002/env.2140. 2012.
. Genetic contribution of catechol-O-methyltransferase variants in treatment outcome of low back pain: a prospective genetic association study. BMC Musculoskeletal Disorders (ISSN 1471-2474). 13 doi: 10.1186/1471-2474-13-76. 2012.
. 2011
The differential disease regulome. BMC Genomics (ISSN 1471-2164). 12 pp 353. doi: 10.1186/1471-2164-12-353. 2011. Fulltekst
. Membranous Expression of Ectodomain Isoforms of the Epidermal Growth Factor Receptor Predicts Outcome after Chemoradiotherapy of Lymph Node-Negative Cervical Cancer. Clinical Cancer Research (ISSN 1078-0432). 17(16) pp 5501-5512. doi: 10.1158/1078-0432.CCR-11-0297. 2011.
. Molecular Disease Map of Bone Characterizing the Postmenopausal Osteoporosis Phenotype. Journal of Bone and Mineral Research (ISSN 0884-0431). 26(8) pp 1793-1801. doi: 10.1002/jbmr.396. 2011.
. 2010
The Genomic HyperBrowser: inferential genomics at the sequence level. Genome Biology (ISSN 1465-6906). 11(12) doi: 10.1186/gb-2010-11-12-r121. 2010. Prosjekt Arkiv
. Eight genes are highly associated with BMD variation in postmenopausal Caucasian women. Bone (ISSN 8756-3282). 46(3) pp 604-612. doi: 10.1016/j.bone.2009.11.007. 2010.
. Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers. BMC Medicine (ISSN 1741-7015). 8 doi: 10.1186/1741-7015-8-54. 2010.
. 2009
Gene Dosage, Expression, and Ontology Analysis Identifies Driver Genes in the Carcinogenesis and Chemoradioresistance of Cervical Cancer. PLoS Genetics (ISSN 1553-7390). 5(11) doi: 10.1371/journal.pgen.1000719. 2009.
. ADAPTIVE INDEPENDENT METROPOLIS-HASTINGS. The Annals of Applied Probability (ISSN 1050-5164). 19(1) pp 395-413. doi: 10.1214/08-AAP545. 2009. Fulltekst
. 2008
Validation of oligoarrays for quantitative exploration of the transcriptome. BMC Genomics (ISSN 1471-2164). 9 doi: 10.1186/1471-2164-9-258. 2008.
. GSEA-SNP: applying gene set enrichment analysis to SNP data from genome-wide association studies. Bioinformatics (ISSN 1367-4803). 24(23) pp 2784-2785. doi: 10.1093/bioinformatics/btn516. 2008.
. 2007
Cord blood gene expression in infants hospitalized with respiratory syncytial virus bronchiolitis. Journal of Infectious Diseases (ISSN 0022-1899). 196 doi: 10.1086/519168. 2007.
. 2006
Whole blood gene expression in infants with respiratory syncytial virus bronchiolitis. BMC Infectious Diseases (ISSN 1471-2334). 6 doi: 10.1186/1471-2334-6-175. 2006.
. Sampling effects on gene expression data from a human tumour xenograft. Scandinavian Journal of Laboratory Animal Science (ISSN 0901-3393). 33 pp 17-34. 2006.
. 2005
Limitations of mRNA amplification from small-size cell samples. BMC Genomics (ISSN 1471-2164). (6) pp 147. doi: 10.1186/1471-2164-6-147. 2005.
. Genome-wide estimation of transcript concentrations from spotted cDNA microarray data. Nucleic Acids Research (NAR) (ISSN 0305-1048). 33(17) doi: 10.1093/nar/gni141. 2005.
. Bayesian population dynamics of interacting species: Great gerbils and fleas in Kazakhstan. Biometrics (ISSN 0006-341X). 61 2005.
. 2004
Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method. Proteomics (ISSN 1615-9853). 4 pp 2572-2582. 2004.
. 2003
Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance. BMC Genomics (ISSN 1471-2164). 4(11) doi: 10.1186/1471-2164-4-11. 2003. Sammendrag Sammendrag
. Comment on Cowling's "Spatial Methods for Line Transect Surveys". Biometrics (ISSN 0006-341X). 59 pp 186-188. 2003.
. 1998
Wet snow-cover mapping by C- and L-band polarimtric SAR. Ukjent 1998.
.
. 1997
Examples of use of cut to shorten proofs. Ukjent 1997.
. 1995
Segmentation and visualization of brain lesions in multispectral magnetic resonance images. Computerized Medical Imaging and Graphics (ISSN 0895-6111). 19(2) pp 171-173. 1995.
. Automatic recognition of character strings in maps. Ukjent 1995.
. 1993
Methods for updating of model parameters applied within the area of symbol recognition. Ukjent 1993.
. 1991
Weak logic theory. Theoretical Computer Science (ISSN 0304-3975). 79 pp 295-321. 1991.
. Academic literature review
2009
Adaptive registration of remote sensing images using supervised learning. Photogrammetric Engineering and Remote Sensing (ISSN 0099-1112). 75(11) pp 1297-1306. 2009. Fulltekst
. Academic chapter/article/Conference paper
2020
Signals of Death - Post-Diagnostic Single Gene Expression Trajectories in Breast Cancer - A Proof of Concept. In: Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression. (ISBN 978-82-15-04119-3). pp 141-162. doi: 10.18261/9788215041193-2020-09. 2020. Arkiv
. Statistics of Sparsely Sampled Curves. In: Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression. (ISBN 978-82-15-04119-3). pp 95-109. doi: 10.18261/9788215041193-2020-06. 2020. Fulltekst
. 2006
Bayesian process-based modeling of two-channel microarray experiments estimating absolute mRNA concentrations. In: Bayesian Inference for Gene Expression and Proteomics. (ISBN 978-0-521-86092-5). pp 75-97. 2006.
. Academic lecture
2022
Context-Aware Landmark Detection for 2D Cardiac Ultrasound using Graph Convnet. GEVU Research Day; Teams, 5/23/2022.
. 2021
Learning motion of seismic structures without human labelling. Visual Intelligence Days 2021; Oslo, 10/19/2021 - 10/20/2021.
. 2014
Evaluation of binary descriptors for fast and fully automatic identification. International Conference on Pattern Recognition; Stockholm, 8/24/2014 - 8/28/2014.
. 2011
Statistics Forelesning kurs. Introduction to Microarray Technology; Oslo, 5/10/2011.
. 2010
Bayesian estimation of the climate sensitivity based on a simple climate model fitted to global temperature observations. International Workshop on Modern Statistics for Climate Research; Oslo, 2/1/2010 - 2/2/2010.
. Postmenopausal BMD Variation is Strongly Associated with Subsets of MicroRNAs and Other Non-coding RNAs (ncRNAs) Expression Levels. The American Society for Bone and Mineral Research, Annual Meeting, 2010, Toronto, Ontario, Canada, 10/16/2010.
. 2009
A system for adaptive image registration based on supervised learning. ESA-EUSC-JRC 2009, Sixth Conferenece on Image Information Mining, Madrid, 3-5 Nov. 2009, 11/4/2009. Fulltekst
. 2008
Plant food phytochemicals modulate gene expression in human blood cells. 5th European nutrigenomics conference; potsdam, 9/2/2008 - 9/5/2008.
. Adaptive Co-Registration of Remote Sensing Images. ESA-EUSC 2008: Image Information Mining: pursuing automation of geospatial intelligence for environm, 3/6/2008. Fulltekst
. Vehicle Detection in High-Resolution Satellite Images. ESA-EUSC 2008: Image Information Mining: pursuing automation of geospatial intelligence for environm, 3/6/2008. Fulltekst
. 2006
Steps in a microarray study. Seminar on microarray technologies arranged by the Rikshospitalet-Radiumhospitalet Medical Center; Oslo, 11/24/2006.
. Parallelization of TransCount - making MCMC parallel for huge datasets. High Performance Computing for Statistical Inference, Dublin, August 23-25, 2006, 8/23/2006.
. 2005
Model-based estimation of transcript concentrations from spotted microarray data. 25th European Meeting of Statisticians, July 24-28, 2005, Oslo, Norway, 7/24/2005.
. Logic regression used for statistical analysis of SNP data obtained in genetic association studies. Talk at UMB, Ås, 6/14/2005.
. Experimental design and non-random variation. Lecture at the course \Micorarray data analysis\" at the Norwegian Radium Hospital, Oslo,", 5/31/2005.
. 2004
Introduction to experimental design and statistical analysis in genetic association studies. Reach-out day with theme: Statistical service on experimental design and analysis of SNP experiments, 5/1/2004.
. Experimental design, repeated measurements and control spots. Course in analysis of microarray data; Bergen, 2/3/2004.
. Experimental design and non-random variation. Introduction to Microarray Technology; The Norwegian Radium Hospital, Oslo, 11/29/2004.
. 2003
Forsøksdesign for cDNA mikromatriser. Foredrag. Ahus (Universitetssykehuset i Akershus), 12/1/2003.
. Experimental design, repeated measurements and controls. User course in microarray technology; The Norwegian Radium Hospital, Oslo, 5/14/2003.
. Experimental design, repeated measurements and control spots. User course in microarray technology; The Norwegian Radium Hospital, Oslo, 5/14/2003.
. Estimation of absolute mRNA concentrations from cDNA microarrays. Norevent's 3rd Lysebu meeting, 9/1/2003.
. 2002
Investigating the linearity of an RNA-amplification protocol using analysis of variance on data from cDNA microarray experiments. 19th Nordic Conference on Mathematical Statistics, 6/9/2002.
. Bildeanalyse av mikromatrisedata. NOBIMs industriseminar i bildeanalyse. Tønsberg, 10/24/2002.
. 2000
A new method for sub-pixel snow-cover mapping using hyperspectral imagery. NOBIM-konferansen, 6/6/2000. Fulltekst
. 1998
Segmentation and Visualization of Brain Lesions in Multispectral Magnetic Resonance Images. Workshop on Models and Methods for Spatial and Spatio-temporal Data, München,, 10/19/1998.
. 1993
Methods for updating of model parameters applied within the area of symbol recognition. The 8th SCIA Conference; Tromsø, Norway, 1/1/1993.
. 1992
Oppdatering av parameterestimater. Bildebehandlingsseminar; Institutt for Informatikk, Universitetet i Oslo, 11/9/1992.
. Abstract
2018
Distinct subsets of non-coding RNAs, including miRNAs, are associated with BMD in stressed and unstressed bone. Journal of Bone and Mineral Research. 33 pp 228. 2018. Omtale
. Lecture
2019
Maskinlæring i mammografiprogrammet. Fagkonferansen i mammografiprogrammet, 3/28/2019 - 3/29/2019.
. 2018
Advising in a research institute: Challenges and lessons learned. ADVICE 2018, 11/10/2018 - 11/11/2018.
. 2017
Subtle alterations in gene expression detected in blood prior to metastatic lung cancer diagnosis – the NOWAC study. The 24th Norwegian Epidemiology Conference; Tromsø, 11/7/2017 - 11/8/2017.
. Poster
2022
A two-stage mammography classification model using XAI for ROI detection. Visual Intelligence days 2022; Olavsgaard, 9/28/2022 - 9/29/2022.
. A mammography classification model trained from image labels only. NLDL 2022; Online, 1/10/2022.
. Context-Aware Landmark Detection for 2D Cardiac Ultrasound using a Graph Convolution Network. Northern Lights Deep Learning conference, 1/10/2022 - 1/12/2022.
. 2019
Post-diagnostic blood gene expression profiles in breast cancer - NOWAC Post-genome Cohort. NOFE conference; Oslo, 11/13/2019 - 11/14/2019.
. 2018
Transcriptional profiles of whole blood before a diagnosis of ovarian cancer. NOFE-konferansen 2018; Trondheim, 11/14/2018 - 11/15/2018.
. Distinct subsets of non-coding RNAs, including miRNAs, are associated with BMD in stressed and unstressed bone. ASBMR Annual meeting 2018; Montreal, 9/28/2018 - 10/1/2018.
. 2016
Blood gene expression profiles reflect temporality and clinical parameters up to six years before breast cancer diagnosis – The Norwegian. Norsk Forening for epidemiologi; Bergen, 9/26/2016 - 9/27/2016.
. Blood gene expression profiles reflect temporality and clinical parameters up to six years before breast cancer diagnosis – The Norwegian Women and Cancer Post-genome cohort (Kvinner og Kreft-studien). 1st International NTNU Symposium on clinical biomarkers of cancer; Trondheim, 6/16/2016 - 6/17/2016.
. 2012
Constraining climate sensitivity by observations and models. European Geosciences Union General Assembly 2012; Wien, 4/22/2012 - 4/27/2012.
. 2009
Eight Genes are Highly Associated with BMD variation in Postmenopausal Caucasian Women. 31th Annual meeting of the American Society for Bone and Mineral Research Denver Colorado 2009, 9/11/2009 - 9/15/2009.
. 2005
Absolute mRNA concentrations from MA-data. 8th International Meeting of the Microarray Gene Expression Data Society, 9/11/2005.
. Report
2022
Procedures for mammographic screening with machine learning. Norsk Regnesentral. NR-notat SAMBA/17/22. pp 16. 2022.
. Machine learning for screening mammography. Norsk Regnesentral. NR-notat SAMBA/18/22. pp 33. 2022.
. Learning motion of seismic structures without human labelling. Norsk Regnesentral. NR-notat SAMBA/10/22. pp 22. 2022.
. 2021
Machine learning for image-based interpretation of non-verbal communication. Norsk Regnesentral. NR-notat SAMBA/04/21. pp 37. 2021.
. Machine learning for screening mammography. Norsk Regnesentral. NR-notat SAMBA/05/21. pp 52. 2021.
. Machine learning for image-based interpretation of non-verbal communication - Initial version. Norsk Regnesentral. NR-notat SAMBA/04/21. pp 37. 2021.
. 2020
Deep learning in seismic interpretations - Development and experiments 2020. Norsk Regnesentral. NR-notat SAMBA/51/20. pp 26. 2020.
. Machine learning for screening mammography - Initial analyses on a first limited dataset. Norsk Regnesentral. NR-notat SAMBA/16/20. pp 45. 2020.
. 2019
Estimation of rock cuttings size from images. Norsk Regnesentral. NR-notat SAND/02/2019. pp 43. 2019.
. Deep learning in seismic interpretation. Norsk Regnesentral. NR-notat SAMBA/49/19. pp 39. 2019.
. Deep learning for ultrasound images - next steps. Norsk Regnesentral. NR-notat SAMBA/48/19. pp 55. 2019.
. BLOBREC – a blood-based test for breast cancer Analyses of test properties in the years before and after diagnosis. Norsk Regnesentral. NR-notat SAMBA/27/19. pp 17. 2019. Fulltekst
. Parity and breast cancer Gene expression in blood, normal and tumor tissue. Norsk Regnesentral. NR-notat SAMBA/24/19. pp 30. 2019.
. 2018
Deep learning for ultrasound images. Norsk Regnesentral. NR-notat SAMBA/24/18. pp 92. 2018.
. Parity and breast cancer - Gene expression in blood, normal and tumor tissue. Norsk Regnesentral. NR-notat SAMBA/02/18. pp 25. 2018.
. 2016
Smoothing of forward curves. Norsk Regnesentral. NR-notat SAMBA/25/16. pp 22. 2016.
. Detecting weak gene expression signals in blood before diagnosis of cancer - Comparing breast, ovarian and lung cancer. Norsk Regnesentral. NR-notat SAMBA/28/16. pp 32. 2016.
. Fjerning av støy fra historiske dokumenter. Norsk Regnesentral. NR-notat SAMBA/24/16. pp 38. 2016.
. Parity, breast cancer and gene expression. Norsk Regnesentral. NR-notat SAMBA/19/16. pp 25. 2016.
. Analysis of gene expression in blood before diagnosis of ovarian cancer - Different statistical methods. Norsk Regnesentral. NR-notat SAMBA/10/16. pp 36. 2016. Fulltekst
. Statistical analysis of gene expression in blood before diagnosis of breast cancer. Norsk Regnesentral. NR-notat SAMBA/07/16. pp 39. 2016. Fulltekst
. 2015
Blood-based diagnostic tests for breast cancer:Additional subgroup analyses of the BLOBREC test. Norsk Regnesentral. NR-notat SAMBA/44/15. pp 30. 2015.
. Verification of a blood-based test for breast-cancer (BLOBREC) - Distinguishing breast-cancer patients from population-based controls. Norsk Regnesentral. NR-notat SAMBA/33/15. pp 36. 2015. Fulltekst
. Verifikasjon av strekkoder. Norsk Regnesentral. NR-notat SAMBA/36/15. pp 41. 2015.
. Utvalg av deskriptorer for oppbygging av database. Norsk Regnesentral. NR-notat SAMBA/25/15. pp 27. 2015.
. Bruk av fargedeskriptorer for gjenkjenning av ukeblader. Norsk Regnesentral. NR-notat SAMBA/19/15. pp 30. 2015.
. Curve groups and breast cancer. Norsk Regnesentral. NR-notat SAMBA/18/15. pp 32. 2015.
. 2014
Statistical analysis of gene expression data related to breast cancer diagnosis. Norsk Regnesentral. NR-notat SAMBA/19/14. pp 74. 2014. Fulltekst
. Historisk informasjon fra avisarkiv. Norsk Regnesentral. NR-notat SAMBA 51/14. pp 41. 2014.
. Preprocessing of gene-expression data related to breast cancer diagnosis – extended version. Norsk Regnesentral. NR-notat SAMBA/32/14. 2014.
. Preprocessing of gene-expression data related to breast cancer diagnosis. Norsk Regnesentral. NR-notat SAMBA/35/14. pp 41. 2014.
. Robust klassifikasjon av ukeblader. Norsk Regnesentral. NR-notat SAMBA/17/14. pp 18. 2014.
. 2013
Descriptors and matching for real-time recognition of planar and curved objects. Norsk Regnesentral. NR-notat SAMBA/3/13. pp 39. 2013.
. Metoder og programmer for gjenkjenning av ukeblader. Norsk Regnesentral. NR-notat SAMBA/19/13. pp 18. 2013.
. 2012
Detectors and descriptors for real-time recognition of planar objects. Norsk Regnesentral. NR-notat SAMBA/03/12. pp 23. 2012.
. Detecting beads in time series of DNA-sequencing images. Norsk Regnesentral. NR-notat SAMBA/57/12. pp 35. 2012.
. Image restoration and analysis of biomolecular radioactivity images II. Norsk Regnesentral. NR-notat SAMBA/11/12. pp 48. 2012.
. ProPrice Interface Specification. Norsk Regnesentral. NR-notat SAMBA/29/12. pp 19. 2012.
. Importance Sampling from DNB's Credit Risk Model. Norsk Regnesentral. NR-notat SAMBA/31/12. pp 30. 2012.
. 2011
Bildeanalyse av røntgenbilder til hjelp for aldersvurdering. Norsk Regnesentral. NR-notat SAMBA/43/11. pp 28. 2011. Fulltekst
. Parallellisering av Totalrisiko-programmet ved hjelp av GPU. Norsk Regnesentral. NR-notat SAMBA/13/2011. pp 14. 2011.
. Parallellisering av simulering fra vines. Norsk Regnesentral. NR-notat SAMBA/18/2011. pp 13. 2011.
. Efficient search for biomedical information. Norsk Regnesentral. NR-notat SAMBA/54/11. pp 45. 2011.
. 2010
Parallellisering av Totalrisiko-programmet. Norsk Regnesentral. NR-notat SAMBA/43/10. pp 14. 2010.
. Parallellisering av Kredittrisiko-programmet. Norsk Regnesentral. NR-notat SAMBA/49/10. pp 16. 2010.
. 2009
MIR - Multiple Image Registration, Technical Documentation. Norsk Regnesentral. NR-notat SAMBA/12/09. pp 160. 2009.
. MIR - Multiple Image Registration, Software Documentation. Norsk Regnesentral. NR-notat SAMBA/11/09. pp 138. 2009.
. 2008
CultSearcher – Software Guide, version 2. Computer-assisted detection of potential cultural heritage sites. Norsk Regnesentral. NR-notat SAMBA/15/08. pp 42. 2008. Fulltekst
. Image restoration and analysis of biomolecular radioactivity images. Norsk Regnesentral. NR-notat SAMBA/27/08. pp 34. 2008. Fulltekst
. 2007
CultSearcher - Computer-assisted detection of potential cultural heritage sites. Norsk Regnesentral. NR-notat SAMBA/39/07. pp 39. 2007.
. Road Traffic Snapshot. Norsk Regnesentral. Report at the Norwegian Computing Center 1015. (ISBN 978-82-539-0525-9) pp 71. 2007. Fulltekst
. 2004
Model-based estimation of transcript concentrations from spotted microarray data. Norsk Regnesentral. Report at the Norwegian Computing Center 999. (ISBN 82-539-0507-6) pp 40. 2004. Fulltekst Fulltekst
. glme: a C-program for parameter estimation using Gibbs-sampling in large linear mixed-effects models, with applications to DNA microarray data. Department of Mathematical Sciences, NTNU. Preprint Series in Statistics 2/2004. pp 20. 2004. Fulltekst
. 2003
A Bayesian model for the population dynamics of two interacting species, with application to great gerbils and fleas in south-eastern Kazakhstan. Norsk Regnesentral. Report at the Norwegian Computing Center 994. (ISBN 82-539-0501-7) pp 19. 2003.
. Experimental design and statistical analysis of SNP data obtained in genetic association studies. Norsk Regnesentral. NR-notat SAMBA/28/03. pp 32. 2003. Fulltekst
. 2001
Estimation of a Neyman-Scott process from line transect data by a one-dimensional K-function. Norsk Regnesentral. NR-notat SAMBA/18/01. pp 11. 2001. Fulltekst
. 2000
Plague in Kazakhstan: a bayesian model for the temporal dynamics of a vector-transmitted infectious disease. Norsk Regnesentral. Report at the Norwegian Computing Center 959. (ISBN 82-539-0463-0) pp 20. 2000.
. Locating pipes in cross-profiles - documentation of methods and results. Norsk Regnesentral. NR-notat SAMBA/21/00. pp 23. 2000.
. Locating pipes in cross-profiles - documentation of C++ code. Norsk Regnesentral. NR-notat SAMBA/22/00. pp 29. 2000.
. SnowStar - Teknisk dokumentasjon for SnowStar Server. Norsk Regnesentral. NR-notat SAMBA/29/00. pp 18. 2000.
. SnowStar - Brukerveiledning for SnowStar Server. Norsk Regnesentral. NR-notat SAMBA/28/00. pp 18. 2000.
. 1999
Seismic Attribute Analysis, Part IV. Norsk Regnesentral. NR-notat SAMBA/17/99. pp 76. 1999.
. 1998
Seismic image analysis: 3D texture attributes and classification - part III. Norsk Regnesentral. NR-notat SAMBA/21/98. 1998.
. Snow mapping by multifrequency polarimetric SAR - An investigation of EMISAR data from the EMAC'95 snow campaign in Norway. 934. (ISBN 82-539-0417-7) 1998.
. 1997
Seismic image analysis: 3D texture attributes and classification - part II. Norsk Regnesentral. NR-notat BILD/07/97. pp 60. 1997.
. 1994
Automatic interpretation of incoming mail in administrative environments. Norsk Regnesentral. NR-notat BILD/04/94. pp 21. 1994.
. Segmentation of MR images of the head using a hierarchical method. 881. (ISBN 82-539-0377-4) pp 25. 1994.
. 1993
Segmentation and visualization of brain lesions in multispectral magnetic resonance images. Norsk Regnesentral. (ISBN 82-539-0367-7) pp 37. 1993.
. Assessment of tissue perfusion and characterization of lesions in dynamical MRI using contrast agents and statistical analysis - methodological considerations and clinical applications. Norsk Regnesentral. NR-notat BILD/10/93. pp 70. 1993.
. Diagnostic evaluation of contrast agents in medical imaging - proposals towards quantitative assessment. Norsk Regnesentral. NR-notat BILD/03/93. pp 100. 1993.
. Theory and methods for automatic training and updating. Norsk Regnesentral. NR-notat BILD/08/93. pp 26. 1993.
. Image acquisition and pre-processing methods for machine vision sensors. 864. (ISBN 82-539-0358-8) pp 63. 1993.
. 1992
Analysis of frequency information in echocardiographic radio-frequency data acquired in the presence or absance of a contrast agent (Albunex). Norsk Regnesentral. NR-notat BILD/04/92. 1992.
. An evaluation of statistical modeling in magnetic resonance imaging using images fron the central nervous system aquired with and without a Gladolium-based contrast medium. Norsk Regnesentral. Report at the Norwegian Computing Center 855. (ISBN 82-539-0348-0) pp 47. 1992.
. Multispectral analysis and classification system (cxxmacs): Users manual. Norsk Regnesentral. Report at the Norwegian Computing Center 863. (ISBN 82-539-0356-1) pp 86. 1992.
. Methods for updating of model parameters applied within the area of symbol recognition. Norsk Regnesentral. Report at the Norwegian Computing Center 859. (ISBN 82-539-0352-9) pp 30. 1992.
. Improving statistical image classification by updating model parameters using unclassified pixels. Norsk Regnesentral. Report at the Norwegian Computing Center 857. (ISBN 82-539-0350-2) pp 26. 1992.
. Popular scientific lecture
2009
Introductory microarray course; statistics. , .
. 2008
Introductory microarray course; statistics. , .
. 2006
Finding differentially expressed genes from microarray data. , .
. 2005
Statistics and Bioinformatics. , .
. Funksjonell genomforskning, bioinformatikk og statistikk. Temakveld om bioinformatikk/medisinsk statistikk, Norsk Statistisk Forening avdeling Oslo, 11/30/2005.
. 2004
Course in statistics for molecular biologists. Bergen, 12/7/2004.
. 2002
Klustring av mikromatrisedata. Kurs for Interagon, 4/18/2002.
. Article in business/trade/industry journal
2022
Trajectories of gene expression, seasonal influenza, and within-host seasonal immunity: transfer value to covid-19. medRxiv doi: 10.1101/2022.03.01.22271679. 2022. Fulltekst
. 2003
Introduksjon til analyse av cDNA mikromatrisedata. Norsk Epidemiologi (ISSN 0803-2491). pp 132291-296. 2003.
. 2002
Spatial distribution of whales based on the Norwegian Minke Whale Survey 1996-2001. Ukjent 2002. Fulltekst
. 1997
Use of cut to obtain a characterization of the Kalmar elementary functions. Technical Report Department of Informatics (254, ISBN 82-7368-174-2) 1997.
. 1996
A proof theoretic characterization of the Kalmar elementary functions. Technical Report Department of Informatics (211, ISBN 82-7368-124-6) 1996.
. 1988
Weak logic theory. Doctor Scient Thesis (111) 1988.
. 1986
Theorem proving in classical logic applied within a logic for system specification. Research Report, Department of Informatics, University of Oslo (99) 1986.
. 1985
Bevisføring i klassisk logikk anvendt innenfor en logikk for systemspesifikasjon. Cand. Scient thesis 1985.
. Popular scientific article
2012
Using modelled historical concentrations of short lived climate components to constrain the climate sensitivity. META (ISSN 1890-1956). (2) pp 8-11. 2012.
. 1994
Characterization of lesions in dynamical MRI using contrast agent and statistical analysis. Ukjent pp 123-127. 6/14/1994.
. Reader opinion piece
2006
Bioinformatikk-et tverrfaglig forskningsfelt. Tilfeldig gang, 12/5/2006,
.